Figure 2.
Clinical implications of cognitive reserve. This figure describes the theoretical effects of different levels of AD pathology, on the x-axis, and clinical severity, on the y-axis. When AD pathology is mild, individuals with lower levels of reserve might already appear to be clinically demented, while those with higher reserve might appear clinically normal. At higher levels of pathology, both groups might appear to be clinically demented. Still, those with higher reserve will appear to be less clinically severe than those with lower reserve.