Table 2.
Summary of the cortical thickness results obtained when including number of lifetime attention-deficit/hyperactivity disorder symptoms as a covariate.
| Brain region | Hemisphere | NVtxs | Size (mm2) | X | Y | Z | Max | CWP | |
|---|---|---|---|---|---|---|---|---|---|
| Group comparisons | |||||||||
| HC > CD | Superior temporal gyrus | R | 338 | 154.4 | 64 | −37 | 13 | 3.5 | 0.001 |
| CD > HC | None significant at CWP ≤ 0.001 | ||||||||
| CO-CD > AO-CD and vice-versa | None at CWP ≤ 0.001 | ||||||||
| Correlation with CU traits in the CD group | |||||||||
| Negative correlation | Lingual gyrus | L | 399 | 168.9 | −22 | −54 | −2 | 4.3 | 0.0007 |
| Positive correlation | None at CWP ≤ 0.001 | ||||||||
| Correlation with lifetime CD symptoms in the CD group | |||||||||
| Negative correlation | Inferior parietal lobule | R | 344 | 184.6 | 45 | −64 | 32 | 3.5 | 0.0002 |
| Positive correlation | Inferior frontal gyrus (pars opercularis) | R | 297 | 169.5 | 47 | 25 | 20 | 3.2 | 0.0007 |
Key to abbreviations: AO-CD, adolescence-onset CD; CD, conduct disorder; CO-CD, childhood-onset CD; CU, callous–unemotional; CWP, cluster-wise-P value; HC, healthy control; NVtxs, number of vertices; Max, maximum −log10(P value) in the cluster.